What Is Pre-implantation Genetic Diagnosis (PGD)?

Pre-implantation genetic diagnosis, or PGD, refers to the genetic testing of an embryo for defects before implantation. This procedure was developed in the 1980’s in the United Kingdom as an alternative to other post conception diagnostic procedures, such as an amniocentesis. An amniocentesis can leave a couple with the excruciating decision of whether or not to terminate if there is a severe genetic problem. 

The pre-implantation genetic diagnosis procedure gives women the option to screen the embryo prior to implantation, therefore eliminating the risk of having to terminate the pregnancy should there be a genetic defect. This is a wonderful procedure meant to help and protect infertile, as well as fertile couples. Many fertile couples who have a genetic predisposition often opt to have PGD performed in order to ensure their child is healthy and free of these types of conditions.

PGD is often suggested by a fertility-treatment doctor when you or your partner are a carrier for or have a family history of deadly genetic defects, such as sickle cell, cystic fibrosis, or Rett syndrome, just to name a few. This is also suggested for women whom have had repeated failed pregnancies, already have a child with such a genetic abnormality, or have a partner with certain infertility issues.

During an in vitro fertilization cycle, the eggs are extracted and inseminated with the man’s sperm. After insemination takes place the embryos are formed, it is now that PGD will take place to ensure that only the normal embryos will be used for implantation. This process increases the success rate of live births and decreases the amount of genetic defects.

Pre-implantation genetic diagnosis is not a procedure that makes genetically perfect children. It is simply put in place to ensure that your child does not have to endure a life of suffering and pain due to a genetic abnormality.